Neurotransmitter reuptake and release experiments


Reuptake of neurotransmitters

Reuptake of neurotransmitters into neurons or glia cells represents one of the most important steps in the termination of synaptic neurotransmission.

Experiments into the reuptake of neurotransmitters can be performed with brain tissue, synaptosomes and cell lines


This example shows a screnning of various plant extracts (Stachys, Phlomis, Sideritis) for inhibition of the serotonin transporter.

In addition, we provide several models to study drug-induced modulation of neurotransmitter release (amino acids, catecholamines and their metabolites, biogenic amines).