Sideritis Extracts


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Relevant studies on the CNS activity of Sideritis extracts


European Patent
"altered serotonergic neurotransmission"



European Patent ADHD




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Sideritis
Sideritis, also known as ironwort, mountain tea and shepherd's tea, is a genus of flowering plants well known for their use as herbal medicine, commonly as an herbal tea. They are abundant in the Mediterranean but can also be found in Central Europe and temperate Asia. The genus comprises about 150 species, which are locally used to produce a relaxing tea after daily work.

Sideritis are rich in flavonoids, polyphenols and kauranes, the essential oil is composed of pinenes, limonen, 1,8-cineol and carvacrol.

Experience has shown that mountain tea can be used
in stressful situations to specifically bring body and soul back into balance. This is beneficially supported by its concentration enhancing effect. Beneficial effects have also been observed in anxiety disorders. Sideritis is a great white hope for the treatment of mental disorders such as burnout, stress and mental fatigue, just because its mood balancing effect is hardly affected by undesirable side effects.

Our research showed that mountain tea acts by regulating the various neurotransmitter systems. Especially the serotonin, noradrenaline and dopamine exchange between nerve cells is influenced by Sideritis extracts. Greek mountain tea
exactly has a stimulating and balancing effect on the neurotransmitter systems, but without inducing any unwanted side effects by itself.

We have developed and patented extracts from Sideritis ssp. (Greek Mountain Tea), which have been shown in vitro to be triple monamine reuptake inhibitors. This pharmacological profile of Sideritis extracts suggests their use in the phytochemical therapy of mental disorders associated with a malfunctioning monoaminergic neurotransmission, like depressive disorders, panic attacs, generalised anxiety disorders or the attention-deficit hyperactivity disorder (ADHD). Sideritis extracts may be superior to other plant extract in the therapy of these disorders, since the long-term traditional use in the mediterranean area until now did not reveal side effects of the drug. 

Several animal studies and observational studies with humans confirm this in vitro mechanism of action. You may find some studies relevant for the understanding of the CNS action of Sidertis extracts at the cross references on the left side.

We are convinced of the pharmaceutical potential of Sideritis extract as CNS drugs and search for interested cooperation partners to promote the development of innovative herbal medicines.